the inci denc e of pros tatic intraepi thelial neoplasia in prostatic hyperplasia and pros tatic c arcinoma

نویسندگان

s torabi-nezhad from the department of pathology, shiraz university of medical sciences, shiraz, i.r.lran.

s maftoun

چکیده

prostatic intra-epithelial neoplasia (pin) is considered a precursor of invasive carcinoma, characterized by proliferation and anaplasia of cells lining prostatic ducts and acini. in this study, we applied the pin grading system on one-hundred cases of prostatic carcinoma and one-hundred cases of benign prostatic hyperplasia, then compared the results. 74% of prostatic carcinoma and 51 % of prostatic hyperplasia cases showed pin foci. most of the prostatic carcinomas (61 %) showed foci of high-grade pin including grade ii (46%) and grade iii (15%). in benign prostatic hyperplasia cases, only pin grade i (26%) and grade ii (25%) were seen. it is concluded that pin and invasive adenocarcinoma of prostate are closely associated and the likelihood for coexistence is higher in patients with high grade pin and especially if other factors such as prostate specific antigen and positive findings on sonography are also considered.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

THE INCI DENC E OF PROS TATIC INTRAEPI THELIAL NEOPLASIA IN PROSTATIC HYPERPLASIA AND PROS TATIC C ARCINOMA

Prostatic intra-epithelial neoplasia (PIN) is considered a precursor of invasive carcinoma, characterized by proliferation and anaplasia of cells lining prostatic ducts and acini. In this study, we applied the PIN grading system on one-hundred cases of prostatic carcinoma and one-hundred cases of benign prostatic hyperplasia, then compared the results. 74% of prostatic carcinoma and 51 % of...

متن کامل

(punch Operation) for Small Prostatic Bars and Contracture of the Pros- Tatic Orifice*

In 1836, Mercier first vigorously called attention to the occasional occurrence of obstructions at the prostatic orifice in cases other than prostatic hypertrophy, and gave them the name of valvules du col de la vessie. He described quite accurately the elevation of the median portion of the prostate in the form of a bar, which he said in some cases was due to muscular hypertrophy, and in other...

متن کامل

Compensatory Efforts; A Critique of the Pros and Cons

Compensatory efforts, positive discrimination or reverse discrimination are the terms which nowadays are used in applied ethics for a set of efforts and privileges which are scheduled for compensation of the historical oppressions and discriminations imposed upon some groups and classes in the society. The mentioned oppressions and discriminations may be applied deliberately or inadvertently or...

متن کامل

Pros & Cons

As scientists who are also clinicians, we should approach research work and clinical therapy with an objective attitude, bearing in mind that there are two sides to every theory. In particular, we hope the reader realizes the pros and cons of each situation. We already knew that the patients in the hospital might improve faster with more family contact, but family in the intensive care unit cou...

متن کامل

Pros and Cons of Neutering

Spaying (ovariectomy or ovariohysterectomy) has been shown to reduce unwanted pregnancies, prevent pyometra and decrease the risk of mammary gland tumors in female dogs and cats. However, increased tendency to develop obesity may occur in either species. In dogs, an increased incidence of certain cancers, aggressiveness, sedentary behavior, and urinary incontinence may develop after spaying. Th...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
medical journal of islamic republic of iran

جلد ۱۴، شماره ۱، صفحات ۹-۱۳

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023